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Researchers successfully edit embryo genes with greater precision

Scientists have used base editing to precisely alter genes in human embryos linked to heart disease and hemoglobin production. The technique appears more accurate than earlier CRISPR methods, though researchers say further study is needed to assess potential risks

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Researchers used base editing. Pic COURTESY/Columbia University

Researchers used base editing. Pic COURTESY/Columbia University

Researchers have used base editing to rewrite specific genes in human embryos, targeting genes linked to heart disease and hemoglobin production.

While earlier CRISPR-based editing frequently caused unintended genetic damage, including snipping out wrong genetic bits or destroying entire chromosomes, base editing resulted in meticulously replaced individual DNA letters. 

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